Novocure Reports First Quarter 2024 Financial Results

BMH Summary

Novocure 2024 first-quarter results:

  • Revenue Growth: Total net revenues for the quarter reached $138.5 million, marking a 13% year-over-year increase. This growth was primarily driven by a successful launch in France and improved U.S. approval rates.
  • Global Contributions: The United States, Germany, and Japan contributed $90.5 million, $15.7 million, and $7.8 million, respectively. Other active markets added $19.5 million to the revenue. Additionally, Novocure’s partnership with Zai Lab in Greater China resulted in $4.9 million in revenue.
  • Clinical Trial Success: The METIS Phase 3 clinical trial in brain metastases from non-small cell lung cancer (NSCLC) met its primary endpoint. These positive results will be presented as a late-breaking abstract at ASCO 2024.
  • LUNAR PMA Application: Novocure completed a Day-100 meeting with the U.S. Food and Drug Administration (FDA) for the LUNAR PMA application for TTFields in NSCLC.
  • Financial Position: As of March 31, 2024, Novocure had $870 million in cash, cash equivalents, and short-term investments.
  • Credit Facility Agreement: In May, Novocure entered into a new five-year senior secured credit facility agreement with affiliates of Pharmakon Advisors for up to $400 million. This strengthens the company’s cash position and provides flexibility for future investments.

Quarterly net revenues of $139 million, up 13% year-over-year, with 3,845 active patients on therapy as of March 31, 2024

Phase 3 METIS trial in brain metastases from non-small cell lung cancer met primary endpoint and will be presented as late-breaking abstract at ASCO 2024

LUNAR PMA application for TTFields in NSCLC Day 100 FDA meeting complete

May 02, 2024 07:00 AM Eastern Daylight Time

ROOT, Switzerland–(BUSINESS WIRE)–Novocure (NASDAQ: NVCR) today reported financial results for the quarter ended March 31, 2024. Novocure is a global oncology company working to extend survival in some of the most aggressive forms of cancer by developing and commercializing its innovative therapy, Tumor Treating Fields (TTFields).

“The first quarter was a period of strong execution”Post this

“The first quarter was a period of strong execution,” said William Doyle, Novocure’s Executive Chairman. “In Q1, GBM active patients grew 11%, we announced the METIS Phase 3 clinical trial met its primary endpoint, and we met with the U.S. Food and Drug Administration (FDA) in a Day-100 meeting for the LUNAR PMA application. We have multiple milestones ahead of us in 2024, and I remain grateful for our teams’ dedication and hard work.”

Financial updates for the first quarter ended March 31, 2024:

  • Total net revenues for the quarter were $138.5 million, an increase of 13% compared to the same period in 2023. This increase was primarily driven by our successful launch in France and improved U.S. approval rates.
    • The United States, Germany and Japan contributed $90.5 million, $15.7 million and $7.8 million, respectively, with other active markets contributing $19.5 million.
    • Revenue in Greater China from Novocure’s partnership with Zai Lab totaled $4.9 million.
  • Gross margin for the quarter was 76%.
  • Research, development, and clinical studies expenses for the quarter were $51.6 million, a decrease of 14% from the same period in 2023. This primarily reflects decreased personnel expenses and reduced direct clinical trial expenses driven by the timing of activities within the clinical trial portfolio.
  • Sales and marketing expenses for the quarter were $55.2 million, an increase of 8% compared to the same period in 2023. This primarily reflects sales force expansion and increased marketing activities in anticipation of our potential launch in non-small cell lung cancer.
  • General and administrative expenses for the quarter were $39.5 million, a decrease of 6% compared to the same period in 2023. This primarily reflects lower personnel expenses.
  • Net loss for the quarter was $38.8 million with loss per share of $0.36.
  • Adjusted EBITDA* for the quarter was $(4.6) million.
  • Cash, cash equivalents and short-term investments were $870 million as of March 31, 2024.
  • In May, we entered into a new five-year senior secured credit facility agreement with affiliates of Pharmakon Advisors for up to $400 million, drawn across up to four tranches of $100 million. This non-dilutive, multi-tranche, delayed-draw, debt facility strengthens our cash position and further solidifies our balance sheet while providing valuable flexibility as we invest in our future.

Operational updates for the first quarter ended March 31, 2024:

  • 1,643 prescriptions were received in the quarter, an increase of 10% compared to the same period in 2023. Prescriptions from the United States, Germany and Japan contributed 990, 206 and 91 prescriptions, respectively, with the remaining 356 prescriptions received in other active markets.
  • As of March 31, 2024, there were 3,845 active patients on therapy. Active patients from the United States, Germany and Japan contributed 2,137, 540 and 379 active patients, respectively, with the remaining 789 active patients contributed by other active markets.

Quarterly updates and achievements:

  • In April, we met with the FDA in a Day-100 meeting for the PMA application for Optune Lua in non-small cell lung cancer (NSCLC). The meeting was productive with no indication that the PMA will be referred to an advisory panel. We continue to anticipate the PMA decision in the second half of 2024.
  • In March 2024, we announced the METIS Phase 3 clinical trial met its primary endpoint, demonstrating a statistically significant extension in time to intracranial progression for patients with brain metastases from NSCLC. The METIS trial data will be presented as a late-breaking abstract at the upcoming American Society of Clinical Oncology (ASCO) scientific congress in June.
  • In March, the FDA approved the Investigational New Drug (IND) application for the randomized, Phase 3 KEYNOTE D58 trial. KEYNOTE D58 will explore the use of TTFields therapy together with temozolomide and the immunotherapy pembrolizumab for the treatment of newly diagnosed glioblastoma.
  • In March, an exploratory subgroup analysis of the randomized, Phase 3 INNOVATE-3 trial was selected as a Best Oral Presentation at the European Society of Gynaecological Oncology 2024 Congress. The exploratory analysis found that pegylated liposomal doxorubicin (PLD) -naïve patients randomized to receive TTFields therapy and paclitaxel exhibited median overall survival of 16.0 months compared to 11.7 months in PLD-naïve patients treated with paclitaxel alone.

Anticipated 2024 clinical milestones:

  • Top-line data from Phase 3 PANOVA-3 clinical trial in locally advanced pancreatic cancer (Q4 2024)

Conference call details

Novocure will host a conference call and webcast to discuss first quarter 2024 financial results at 8:00 a.m. EDT today, Thursday, May 2, 2024. To access the conference call by phone, use the following conference call registration link and dial-in details will be provided. To access the webcast, use the following webcast registration link.

The webcast, earnings slides presented during the webcast and the corporate presentation can be accessed live from the Investor Relations page of Novocure’s website, www.novocure.com/investor-relations, and will be available for at least 14 days following the call. Novocure has used, and intends to continue to use, its investor relations website as a means of disclosing material non-public information and for complying with its disclosure obligations under Regulation FD.

About Novocure

Novocure is a global oncology company working to extend survival in some of the most aggressive forms of cancer through the development and commercialization of its innovative therapy, Tumor Treating Fields. Novocure’s commercialized products are approved in certain countries for the treatment of adult patients with glioblastoma, malignant pleural mesothelioma and pleural mesothelioma. Novocure has ongoing or completed clinical trials investigating Tumor Treating Fields in brain metastases, gastric cancer, glioblastoma, liver cancer, non-small cell lung cancer, pancreatic cancer and ovarian cancer.

Headquartered in Root, Switzerland and with a growing global footprint, Novocure has regional operating centers in Portsmouth, New Hampshire and Tokyo, as well as a research center in Haifa, Israel. For additional information about the company, please visit Novocure.com and follow @Novocure on LinkedIn and Twitter.

*Non-GAAP Financial Measurements

We measure our performance based upon a non-U.S. GAAP measurement of earnings before interest, taxes, depreciation, amortization and shared-based compensation (“Adjusted EBITDA”). We believe Adjusted EBITDA is useful to investors in evaluating our operating performance because it helps investors compare the results of our operations from period to period by removing the impact of earnings attributable to our capital structure, tax rate and material non-cash items, specifically share-based compensation.

Forward-Looking Statements

In addition to historical facts or statements of current condition, this press release may contain forward-looking statements. Forward-looking statements provide Novocure’s current expectations or forecasts of future events. These may include statements regarding anticipated scientific progress on its research programs, clinical trial progress, development of potential products, interpretation of clinical results, prospects for regulatory approval, manufacturing development and capabilities, market prospects for its products, coverage, collections from third-party payers and other statements regarding matters that are not historical facts. You may identify some of these forward-looking statements by the use of words in the statements such as “anticipate,” “estimate,” “expect,” “project,” “intend,” “plan,” “believe” or other words and terms of similar meaning. Novocure’s performance and financial results could differ materially from those reflected in these forward-looking statements due to general financial, economic, environmental, regulatory and political conditions and other more specific risks and uncertainties facing Novocure such as those set forth in its Annual Report on Form 10-K filed on February 22, 2024, and subsequent filings with the U.S. Securities and Exchange Commission. Given these risks and uncertainties, any or all of these forward-looking statements may prove to be incorrect. Therefore, you should not rely on any such factors or forward-looking statements. Furthermore, Novocure does not intend to update publicly any forward-looking statement, except as required by law. Any forward-looking statements herein speak only as of the date hereof. The Private Securities Litigation Reform Act of 1995 permits this discussion.

Consolidated Statements of Operations
USD in thousands (except share and per share data)
 
  Three months ended March 31, Year ended
December 31,
  2024 2023 2023
  Unaudited Audited
Net revenues $138,503  $122,182  $509,338 
Cost of revenues  33,689   29,614   128,280 
Gross profit  104,814   92,568   381,058 
       
Operating costs and expenses:      
Research, development and clinical studies  51,598   59,704   223,062 
Sales and marketing  55,206   51,169   226,809 
General and administrative  39,530   41,944   164,057 
Total operating costs and expenses  146,334   152,817   613,928 
       
Operating income (loss)  (41,520)  (60,249)  (232,870)
Financial income (expenses), net  9,878   9,169   41,130 
       
Income (loss) before income taxes  (31,642)  (51,080)  (191,740)
Income taxes  7,118   1,981   15,303 
Net income (loss) $(38,760) $(53,061) $(207,043)
       
Basic and diluted net income (loss) per ordinary share $(0.36) $(0.50) $(1.95)
Weighted average number of ordinary shares used in computing basic and diluted net income (loss) per share  107,266,198   105,667,072   106,391,178 
Consolidated Balance Sheets
USD in thousands (except share data)
 
March 31,
2024
 December 31,
2023
 Unaudited Audited
ASSETS   
CURRENT ASSETS:   
Cash and cash equivalents$453,763 $240,821
Short-term investments 416,384  669,795
Restricted cash 3,600  1,743
Trade receivables, net 65,091  61,221
Receivables and prepaid expenses 21,479  22,677
Inventories 42,391  38,152
Total current assets 1,002,708  1,034,409
LONG-TERM ASSETS:   
Property and equipment, net 58,917  51,479
Field equipment, net 11,911  11,384
Right-of-use assets 32,994  34,835
Other long-term assets 14,899  14,022
Total long-term assets 118,721  111,720
TOTAL ASSETS$1,121,429 $1,146,129
Consolidated Balance Sheets
USD in thousands (except share data)
 
 March 31,
2024
 December 31, 2023
 Unaudited Audited
LIABILITIES AND SHAREHOLDERS’ EQUITY   
CURRENT LIABILITIES:   
Trade payables$84,316  $94,391 
Other payables, lease liabilities and accrued expenses 75,914   84,724 
Total current liabilities 160,230   179,115 
LONG-TERM LIABILITIES:   
Long-term debt, net 569,652   568,822 
Long-term leases 25,608   27,420 
Employee benefit liabilities 6,566   8,258 
Other long-term liabilities 18   18 
Total long-term liabilities 601,844   604,518 
TOTAL LIABILITIES 762,074   783,633 
    
COMMITMENTS AND CONTINGENCIES   
    
SHAREHOLDERS’ EQUITY:   
Share capital –   
Ordinary shares no par value, unlimited shares authorized; issued and outstanding:107,603,774 shares and 107,075,754 shares at March 31, 2024 (unaudited) and December 31, 2023, respectively     
Additional paid-in capital 1,387,765   1,353,468 
Accumulated other comprehensive income (loss) (4,147)  (5,469)
Retained earnings (accumulated deficit) (1,024,263)  (985,503)
TOTAL SHAREHOLDERS’ EQUITY 359,355   362,496 
TOTAL LIABILITIES AND SHAREHOLDERS’ EQUITY$1,121,429  $1,146,129 
Non-U.S. GAAP financial measures reconciliation
USD in thousands
 
  Three months ended March 31,
  2024 2023 % Change
Net income (loss) $(38,760) $(53,061) (27)%
Add: Income tax  7,118   1,981  259%
Add: Financial expenses (income), net  (9,878)  (9,169) 8%
Add: Depreciation and amortization  2,815   2,722  3%
EBITDA $(38,705) $(57,527) (33)%
Add: Share-based compensation  34,084   39,084  (13)%
Adjusted EBITDA $(4,621) $(18,443) (75)%

Contacts

Investors & Media:
Ingrid Goldberg
investorinfo@novocure.com
media@novocure.com
610-723-7427

Original press release can be found here.